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Successful Management of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy and Immune Reconstitution Syndrome in a Patient With Multiple Sclerosis
2010
Archives of Neurology
Objective: To describe a case of successful clinical management of natalizumab-associated progressive multifocal leukoencephalopathy (PML) and immune reconstitution syndrome (IRIS) in a patient with multiple sclerosis. Design: Case report. Setting: University hospital. Patient: A 41-year-old woman with relapsingremitting multiple sclerosis developed PML after 29 natalizumab infusions. Interventions: Immediate plasma exchange was combined for removal of natalizumab with application of mefloquine
doi:10.1001/archneurol.2010.157
pmid:20625069
fatcat:o2d5rhj2aja3lkfs3mxx7zohy4