Renal Transplantation Studies in Genetic Hypertension

Olaf Grisk, Rainer Rettig
2001 Physiology  
Renal cross-transplantation experiments revealed that the kidney plays a key role in primary hypertension. Advanced animal breeding strategies leading to the generation of congenic and consomic rat strains combined with renal transplantation experiments will allow researchers to quantify the contribution of renal and extrarenal mechanisms to the development of genetic forms of hypertension.
doi:10.1152/physiologyonline.2001.16.6.262 pmid:11719601 fatcat:kzmgvm2yonbbtkuzyar2nmaasy