DNA duplex stabilization in crowded polyanion solutions

Imran Khimji, Jeehae Shin, Juewen Liu
2013 Chemical Communications  
The melting temperature of duplex DNA is much higher in 5 polyanions than that in non-ionic polymers with similar ionic strength, suggesting an additional electrostatic contribution on top of the excluded volume effect. Biological fluids and the cytoplasm contain concentrated biopolymers such as nucleic acids and proteins. They occupy 10
doi:10.1039/c2cc38627e pmid:23302897 fatcat:r4kpl4edbrgvbokokf5gzobqpe