ABSTRAK Persalinan adalah proses alami dan menimbulkan nyeri, namun banyak ibu yang tidak bisa menahan rasa nyeri tersebut karena dipengaruhi oleh stres. Terapi non farmakologi yang dapat digunakan untuk mengurangi rasa nyeri adalah Murotal Al-Qur'an. Terapi ini dapat menstimulasi gelombang delta yang menyebabkan pendengar dalam keadaan tenang, tentram dan nyaman sehingga hypopfise dan hypothalamus mengeluarkan β-Endorphin sebagai analgesik alamiah. Tujuan penelitian ini membuktikan bahwa

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... murotal Al-Qur'an Surat Ar-rahman dapat meningkatkan kadar β-Endorphin dan menurunkan intensitas nyeri persalinan pada kala I fase aktif. Penelitian ini dilakukan di rumah sakit Abunawas Kendari dan Laboratorium Fakultas Kedokteran UNHAS. Desain penelitian Quasi-Experimental dengan pendekatan Pre-Experimental design One-Group Pre-test-Post-test. Pengambilan sampeldengan tehnik purposive sampling sebanyak 30 orang. Pengukuran kadar β-Endorphin dilakukan dengan ELISA kit dan intensitas nyeri persalinan diukur dengan menggunakan Bourbannis pain scale. Analisis data dengan Kolmogorov-Smirnov dan uji t berpasangan. Hasil penelitian menunjukkan ada penurunan signifikan intensitas nyeri sebelum (6,80±1,52) dibandingkan sesudah (3,37±1,79) pemberian terapi murotal Al-Qur,an surat Ar-rahman selama 25 menit (p=0,000). Terapi murotal Al-Qur'an juga menunjukkan peningkatan signifikan (p=0,000) kadar β-Endorphin sebelum perlakuan (1053,6±606,32ng/L) dan setelah perlakuan (1813,6±546,78ng/L). Dapat disimpulkan bahwa pemberian terapi murotal Al-Qur'an dapat menurunkan intensitas nyeri dan meningkatkan kadar β-Endorphin. Kata Kunci: β-Endorphin, intensitas nyeri, kala I fase aktif, murotal surat Arrahman ABSTRACT Childbirth is a natural process and causes pain however many mothers affected by stress couldn't with stand the pain. Al Qur'an recital as a non-pharmacological therapy can be used to reduce pain. This therapy stimulates delta waves which make the listener more relax, peaceful, and comfortable so that hypopfise and hypothalamus produce β-endorphin as natural analgesic. This research aims to prove that Al Qur'an surah Arrahman recital therapy may increase β-endorphin level and reduce child birth pain intensity on active phase in first stage. The research was conducted at Abunawas Kendari regional hospital and medical faculty laboratory of UNHAS. The research used Quasi-Experimental with Pre-Experimental design One-Group Pre-test-Post-testapproach. The samples were 30 mothers by using purposive sampling methods. β-Endorphinwas measured by using ELISA kit and childbirth pain intensity was measured by using Bourbannis pain scale. Data were analyzed with Kolmogorov-Smirnov and paired t test. The result shows there was a significant decrease in pain intensity before (6,80±1,52) than after (3,37±1,79) the recital therapy for 25 minutes (p=0,000). Qur'an recital therapy also showed a significant increase (p=0,000) on β-Endorphin levels before treatment (1053,6 ± 606,32ng/L) and after treatment (1813,6 ± 546,78ng/L). It can be concluded that Qur'an recital therapy can reduce pain intensity and increase levels of β-Endorphin.