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The work of breathing in a nonlinear model of respiratory mechanics

A. Athanasiades, F. Ghorbel, J.W. Clark, S.C. Niranjan, C.H. Liu, J.B. Zwischenberger, A. Bidani
Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)  

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Analytical expressions are derived for the work of breathing (WOB) and are subsequently evaluated for a typical pulmonary function laboratory test that includes tidal breathing, panting and the forced vital capacity maneuvers. The analysis is based on a nonlinear model of respiratory mechanics that successfully mimics information presented in the conventional Campbell diagram, which is often used to graphically estimate WOB. In addition, the model reveals the partitioning of elastic-WOB among the collapsible airways and lung. I(eyw0Td.s-
doi:10.1109/iembs.1997.758783 fatcat:bh5u7e2z7zg77njdl5i2mqvp7y
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A. Athanasiades, F. Ghorbel, J.W. Clark, S.C. Niranjan, C.H. Liu, J.B. Zwischenberger, A. Bidani. "The work of breathing in a nonlinear model of respiratory mechanics." Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)