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Hardware performance counters are used as effective proxies to estimate power consumption and runtime. In this paper we present a performance counter-based power and performance modeling and optimization method, and use the method to model four metrics: runtime, system power, CPU power and memory power. The performance counters that compose the models are used to explore some counterguided optimizations with two large-scale scientific applications: an earthquake simulation and an aerospacedoi:10.1109/ipdpsw.2016.78 dblp:conf/ipps/WuT16 fatcat:qmlnku6wbbapzmd43vofvasegm