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Biological Monitoring of Exposure to Organic Solvent Vapors II. Simulation Studies using a Physiological Pharmacokinetic Model for m-Xylene
1991
The relationship between external and internal doses of m-xylene afid the effects of body weight, body fatcontent, sex, and phys'ical activity on the pharmacokinetics of m-xylene were studied using a physiological simulation model. 1. Adow exposure concentrations, equal time-weighted average (TWA) concentrations gave almost the same intemal dose of m-xylene. 2. The m-xylene concentration in the blood increased continuously with increasing m-xylene concentration in inhaled air. By contrast, the
doi:10.34429/00003152
fatcat:k3dgwtoydrcsza62aqj5fozbzm