HUMULUS LUPULUS L. (HOPS) - A VALUABLE SOURCE OF COMPOUNDS WITH BIOACTIVE EFFECTS FOR FUTURE THERAPIES

Jana Olšovská, Vanda Boštíková, Martin Dušek, Vladimíra Jandovská, Kateřina Bogdanová, Pavel Čermák, Pavel Boštík, Alexandr Mikyska, Milan Kolář
2016 Military Medical Science Letters  
Hops are a well-known source of resins, essential oils and polyphenolic substances, such as proanthocyanidins or prenylflavonoids with significant representatives of xanthohumol, isoxanthohumol, and 8-prenylnaringenine, and represent an essential ingredient in beer production. Recently, however, many additional bioactive effects of hop compounds have been investigated. A systematic review of the structure-function relationship between the individual hop-derived compounds and their bio-activity
more » ... as been lacking. In this review we summarize some recent findings in this area from reports from our as well as other studies. It shows multiple bio-medical effects of the individual hop derived compounds, which can act individually, or in a synergistic manner. The hops can serve as a source of bio-active compounds in phyto-medicine and as such, more attention and detailed studies are warranted to utilize the broad spectrum of effects of individual compounds in future treatments. An increasing number of pathogenic strains of bacteria (and viruses) resistant to different types of antimicrobials poses a major medical problem. Secondary metabolites of hops have been described
doi:10.31482/mmsl.2016.004 fatcat:d5t5jlmsavhwrdggecl2vrdu5u