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Aclidinium bromide inhibits proliferation, migration and invasion but promotes apoptosis of human glioma cells via PI3K/AKT signaling pathway
2018
Neoplasma (Bratislava)
This study investigates the anti-cancer potential of Aclidinium bromide (INN) in glioblastoma. Glioblastoma cell lines U251 and U87 were treated with INN and its effects on cell migration and invasion were assessed by transwell migration and invasion assays., The effects of INN on proliferation and apoptosis were detected by CCK-8 kit and flow cytometry, and Western blotting determined anti-apoptotic proteins and signaling pathway changes. The results show that INN effectively suppressed
doi:10.4149/neo_2018_171117n705
pmid:29940755
fatcat:zsjgwqhi4vcivheas46pdvowi4