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Lecture Notes in Computer Science
Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often used to investigate functional groups of genes. In particular, when one of the genes is a transcription factor (TF), the co-expression-based interaction is interpreted, with caution, as a direct regulatory interaction. However, any particular TF, and more importantly, any particular regulatory interaction, is likely to be active onlydoi:10.1007/978-3-642-04241-6_12 fatcat:7e5q6vvkvbavlagt4b6qvf6ivq