The delivery of drug substance through the mucosa (oral) presents a great opportunity but also poses continuing challenges. Xerostomia, the excessive dryness of mouth, and reduction in the saliva secretion poses a debilitating condition for majority of patients. Evaluation of xerostomia starts with a careful and complete examination of mouth. Numerous treatments are available for the management of xerostomia including salivary stimulants, saliva substitutes, topical agents and sialogogues for

more »

... stemic effect. The purpose of this article is to investigate the existing knowledge on management and cureing patients affected by dryness of mouth or with altered salivation.