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Molecular Mechanisms Underlying the Protective Effect of Telmisartan in Non-Alcoholic Fatty Liver Disease: Role of Proinflammatory Enzymes
Egyptian Journal of Basic and Clinical Pharmacology
Non-alcoholic fatty liver disease (NAFLD) is an increasingly recognized condition that may progress to end stage liver cell failure. There is as yet no clearly established therapy for prevention or treatment of NAFLD. Telmisartan, an angiotensin II receptor blockers and partial agonist on peroxisome proliferative activated receptor-gamma (PPAR-γ), showed a promising protective effect in NAFLD. Aim: The present study explored the mechanism(s) of the protective effect of telmisartan on NAFLD withdoi:10.11131/2011/101326 fatcat:5xmwfvp6lvdzzcb5f3y55ifmva