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Functional genomic and high-content screening for target discovery and deconvolution
2012
Expert Opinion on Drug Discovery
Introduction-Functional genomic screens apply knowledge gained from the sequencing of the human genome toward rapid methods of identifying genes involved in cellular function based on a specific phenotype. This approach has been made possible through the use of advances in both molecular biology and automation. The utility of this approach has been further enhanced through the application of image-based high content screening, an automated microscopy and quantitative image analysis platform.
doi:10.1517/17460441.2012.711311
pmid:22860749
pmcid:PMC3954969
fatcat:3gk7e5f7ynezpoj37ewh46sf2a