Acute Right Iliac Fossa Pain is a common symptom which has shown diagnostic difficulties for the surgical emergency clinic. A White Blood Cells test is required for Acute Right Iliac Fossa Pain diagnosis. In this study, we aimed to clarify the importance of Differential White Blood Cells test for Acute Right Iliac Fossa Pain diagnosis. The present observational study was conducted in in Heet General Hospital over a period of five months included 62 patients from both genders of different ages

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... -45 years) who were suffering from Acute Right Iliac Fossa Pain. All patients were subjected to Differential White Blood Cells test which was carried out in the hospital laboratory using (Hematology Pentra 60 Series HORIBA ABX SAS). A statistical analysis were then run using ANOVA and LSD tests. The analysis have shown the means of each type as follow; NEU (8.3516), LYM (31.2984), MON, (6.1952), GRA (62.6790) 10^3/mm3. Also, a comparison among all the WBCs types and also between and within groups was performed using one and two ways Analysis of Variance ANOVA tests which have shown that there are significant differences of all differentials WBCs types. p<0.05 was considered statistically significant. Based on our findings, it can be clearly stated that Differential White Blood Cells tests (not only WBC) are very important for the clear diagnosis of Acute Right Iliac Fossa Pathology.