A Retrospective Analysis of Skin Bacterial Colonisation, Susceptibility and Resistance in Atopic Dermatitis and Impetigo Patients

L Salah, J Faergemann
2015 Acta Dermato-Venereologica  
Atopic dermatitis (AD) and impetigo are skin conditions where bacterial colonisation and infection, especially with Staphylococcus aureus play an important role. We compared skin bacterial population, resistance patterns and choice of antimicrobial agents in patients diagnosed with AD and impetigo during 2005 and 2011 in our department. Number of positive cultures in the AD group were 40 and 53 in 2005 and 2011, with S. aureus found in 97.5% and 100%, respectively. Differences in resistance
more » ... s in resistance were marginal. In impetigo, S. aureus was found in all 70 patients in impetigo patients in 2005 and all 40 patients in 2011. Antibiotic resistance to specifically fusidic acid was more common in 2005 (22.8%) versus 2011 (5%) (p = 0.078). The most commonly used oral antimicrobial was cefadroxil (in 57.5% and 52.8% of AD and 58.6% and 35% of impetigo patients in 2005 and 2011, respectively). Our observations confirm the high prevalence of S. aureus in both diseases and, interestingly, show a declining resistance trend in impetigo.
doi:10.2340/00015555-1996 pmid:25367860 fatcat:uoeaq3r2rrbmldegwvl74xsv3m