Transplantatnierenarterienstenose: Perkutane transluminale Angioplastie als First-Line-Therapie

Stephanie Kuchlbauer
2009
In our transplant centre 11 of 264 patients (4,17%) who underwent kidney transplantation were diagnosed with significant transplant renal artery stenosis. In addition to that, TRAS occurred in two elsewhere transplanted patients who had their follow-up examinations in our centre. Either a rise of the creatinine level or/and worsened systemic hypertension or routine examination with color doppler sonography were the indication to perform an angiography which was extended to percutaneous
more » ... rcutaneous transluminal angioplasty after the diagnosis of TRAS was confirmed in all of these patients. The immediate success rate for PTA was 92,3% (12/13). Only one patient with a kinking of the renal artery had to undergo surgery to restore renal function. No complications occurred after the interventions. The patients were monitored for a mean observation time of 33,15 months. The creatinine levels were lower after the intervention (mostly significantly), the effect on blood pressure was immediate, but not long-lasting, whereas the dose of the prescribed drugs decreased within time. A rise of the hemoglobine level could also be seen. So the effect of the PTA is not only temporarily, but mostly long-lasting, which means it should be first-line treatment in TRAS except for kinking stenosis which should be treated by surgery.
doi:10.5283/epub.12082 fatcat:hj6oqkhbznf27gmi7m5bp5aw2y