RESIDENT PHYSICIAN AND SUPERINTENDENT TO THE LONDON COUNTY ASYLUM, CLAYBURY. GENTLEMEN,-The object of this address is to demonstrate that with the progress of civilisation mental breakdown becomes more serious and more frequent and the varieties of insanity are more chronic and less curable than in the early days of a century ago, when life was simpler and men were more content. It is a universal law that the most highly integrated functions of vital organi&ms are the most apt to suffer

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... ent. The human mind-the most highly evolved process in relation to matter-has from the earliest times been subject