A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface

Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan (+8 others)
2015 Cell  
Graphical Abstract Highlights d BioID conducted on 58 centriole, satellite, and ciliary transition zone proteins d Centriole-cilium interface map comprises >1,700 unique components, >7,000 interactions d Microscopy and functional screens confirm new centriolecilium regulatory modules d Dynamic modulation of interaction landscape observed during ciliogenesis program
doi:10.1016/j.cell.2015.10.065 pmid:26638075 pmcid:PMC5089374 fatcat:av27mndmrbcbldbygtus3mc5ay