Intraluminal Prucalopride Increases Propulsive Motor Activities in the Human Colon [post]

Mitra Shokrollahi, Xuan Yu Wang, Natalija Milkova, Jan Huizinga, Ji Hong Chen
2020 unpublished
High-resolution colonic manometry and biopsy immunohistochemistry revealed that 5-HT4 receptors in the lumen of the human colon are present exclusively on enterochromaffin cells and the 5-HT4 receptor agonist prucalopride, evokes all major propulsive motor patterns, associated with significant anal sphincter relaxation, when given intraluminally.
doi:10.22541/au.159015539.92461507 fatcat:qtzuimzcxfhqvl4qifkbky75my