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13: Direct Intra Bone Transplant of Unrelated Cord Blood Cells Is Associated with Fast and Complete Hematologic Recovery
2007
Biology of Blood and Marrow Transplantation
therapeutics. We have attempted to define elements of a hematopoietic stem cell niche by focusing on the endosteal surface where some stem cells are known to localize in the adult mammal. Using genetic models altering features of the bone or the stem cell response to bone elements, we and others have begun to characterize components of the endosteal stem cell niche. The molecular interactions governing the effects of the niche provide potential targets for drug based therapies and some of these
doi:10.1016/j.bbmt.2007.08.021
fatcat:fgx7ssmshbeezl6wgb76xwbvqm