A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Effective Biophysical Modeling of Cell Free Transcription and Translation Processes
2020
Frontiers in Bioengineering and Biotechnology
Transcription and translation are at the heart of metabolism and signal transduction. In this study, we developed an effective biophysical modeling approach to simulate transcription and translation processes. The model, composed of coupled ordinary differential equations, was tested by comparing simulations of two cell free synthetic circuits with experimental measurements generated in this study. First, we considered a simple circuit in which sigma factor 70 induced the expression of green
doi:10.3389/fbioe.2020.539081
pmid:33324619
pmcid:PMC7726328
fatcat:pzemdrnygbcidl57mvu4kichvi