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Learning-accelerated Discovery of Immune-Tumour Interactions
[article]
2019
bioRxiv
pre-print
We present an integrated framework for enabling dynamic exploration of design spaces for cancer immunotherapies with detailed dynamical simulation models on high-performance computing resources. Our framework combines PhysiCell, an open source agent-based simulation platform for cancer and other multicellular systems, and EMEWS, an open source platform for extreme-scale model exploration. We build an agent-based model of immunosurveillance against heterogeneous tumours, which includes spatial
doi:10.1101/573972
fatcat:ftdxzyzuungu3lij5hmdmcktk4