Primitive neuroectodermal tumor of the kidney: a rare case

R. Pandey, R. Batra, P. Dhaigude, D. Gupta
2021 African Journal of Urology  
Background Primitive neuroectodermal tumor commonly occurs in bones and is equivalent to Ewing's sarcoma. Very few cases have been reported in the literature and they had a very different presentation and very aggressive behavior. Case presentation We present a case of a young 23-year-old male who presented with complaints of pain in left lumbar region of abdomen since 8 months and hematuria off and on. CT scan of the abdomen was done which revealed a large heterogeneously enhancing mass lesion
more » ... in the left lumbar region arising from the superior and mid-pole of left kidney showing multiple non-enhancing necrotic areas. A diagnosis of left renal cell carcinoma was kept. Through the transperitoneal approach, the left kidney was approached and a left radical nephrectomy was done. The histopathology report revealed the tumor cells to be positive for CD99 and focally positive for Vimentin and negative for cytokeratin thereby making a diagnosis of primary neuroectodermal tumor (PNET). Conclusions Renal PNET is a rare renal malignancy that should be kept in the differential diagnosis of a renal SOL especially when it is a presenting feature in adolescent and young adult. It has a very aggressive course and multimodal therapy has to be considered in its treatment
doi:10.1186/s12301-021-00138-w doaj:26eb6e15a7f840e793b85b04a1c75165 fatcat:lnhrxxhy2vfgza6ymysvlnksze