A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2015; you can also visit the original URL.
The file type is application/pdf.
Cross validation of pooling/resampling GWAS using the WTCCC data
2015
Molecular Biology and Genetic Engineering
Preserved Fulltext
Recently, we presented a new method of pooling/resampling genome-wide association study (prGWAS) that uncovered new and known loci associated to Alzheimer's disease. In here, we contrast this method with the Welcome Trust Case Control Consortium (WTCCC) data, a well-known GWAS on seven human complex diseases. Our results suggest that prGWAS can be considered an efficient, specific, and accurate alternative to the conventional GWAS approach at a fraction of the genotyping cost, and provide
doi:10.7243/2053-5767-3-1
fatcat:eeb4tkk2bjgkfivmexfsqo7nuu