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Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer
2014
OncoTarget
The therapeutic response and clinical outcome of patients diagnosed with the same cancer type and that receive identical treatment is highly variable to reflect the genetic heterogeneity within tumor cells. Non-coding RNAs (ncRNAs) are recently discovered molecules that regulate eukaryotic gene expression and represent a significant advance towards a better understanding of the mechanisms that govern cellular growth. NcRNAs are essential for the proper regulation of cell proliferation and
doi:10.18632/oncotarget.2469
pmid:25275300
pmcid:PMC4226665
fatcat:xbxyk3zygfevpjea5q35rhrowa