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The present paper is based upon observations and experiments made on 300 mice, obtained in the laboratories of the Imperial Cancer Research Fund since the summer of 1908, and in which cancer had developed spontaneously. Excluding lung adenomata, lymphomata, and sebaceous adenomata there remain 288 mice in which 350 tumours were observed, microscopical examination showing that they were to be regarded as true new growths. When these tumours were first observed, i.e. at the time of entering themdoi:10.1098/rspb.1911.0036 fatcat:3j3kg7wdwrdoxlsvdhr242ni4q