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Purpose: This study presents how a clinical decision support system can help in prescription and knowledge acquisition processes. Design/methodology/approach: An integrated Electronic Medical Records System (iEMRS) is designed to enhance the decision support quality in prescription. Findings: By evaluating the system performance through 135 prescription records collected from a Hong Kong medical organization, iEMRS shows a satisfactory result in suggesting medicines that is properly the same asdoi:10.1108/13287261211255347 fatcat:ij7jkrfimbaw5hrkvwvdi7cmwe