PTU-009 Long-term effects of obeticholic acid in patients with primary biliary cholangitis on inflammatory markers

Gideon M Hirschfield, Frederik Nevens, Mitchell L Shiffman, Joost PH Drenth, Christopher L Bowlus, Victor Vargas, Pietro Andreone, Stephen Ryder, Alexander Liberman, Elizabeth Smoot Malecha, Leigh MacConell, Michael Trauner
2019 Posters   unpublished
Conclusion In conclusion, the MMP28 gene knockout effect and the change of gut microbiome upon changing living environments influence the metabolic profile through modulations in the insulin and FXR signalling pathways.
doi:10.1136/gutjnl-2019-bsgabstracts.218 fatcat:tn6edk7msndgzez6idsqjqodgq