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Export of β-Lactamase Is Independent of the Signal Recognition Particle
Journal of Biological Chemistry
In Escherichia coli, three different types of proteins engage the SecY translocon of the inner bacterial membrane for translocation or insertion: 1) polytopic membrane proteins that prior to their insertion into the membrane are targeted to the translocon using the bacterial signal recognition particle (SRP) and its receptor; 2) secretory proteins that are targeted to and translocated across the SecY translocon in a SecA-and SecBdependent reaction; and 3) membrane proteins with largedoi:10.1074/jbc.m300929200 pmid:12682042 fatcat:gg2esyj5cfdltfuviic3xx63xm