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SNARE complex-mediated degranulation in mast cells
2012
Journal of Cellular and Molecular Medicine
Mast cell function and dysregulation is important in the development and progression of allergic and autoimmune disease. Identifying novel proteins involved in mast cell function and disease progression is the first step in the design of new therapeutic strategies. Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a family of proteins demonstrated to mediate the transport and fusion of secretory vesicles to the membrane in mast cells, leading to the subsequent
doi:10.1111/j.1582-4934.2011.01443.x
pmid:21880114
pmcid:PMC3822836
fatcat:6bu6nuex4bggzpm5aorccmhazq