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Lactic Acid: An Efficient and Green Catalyst for the One-Pot Five-Components Synthesis of Highly Substituted Piperidines
Polyfunctionalized heterocyclic compounds have an important role in the drug discovery process and analysis of drugs in late development. Piperidines and their analogues have received attention owing to their biological activities, because of the importance of these heterocycle compounds, there is still a need to improve the ways for green synthesis of these compounds. In this study, lactic acid was applied as a green and efficient catalyst for the one-pot five-component synthesis of highlydoi:10.6084/m9.figshare.4483727.v1 fatcat:ky2rfyl7yraotixk3cdb2a4csa