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Optimizing Scoring Function of Protein-Nucleic Acid Interactions with Both Affinity and Specificity
2013
PLoS ONE
Protein-nucleic acid (protein-DNA and protein-RNA) recognition is fundamental to the regulation of gene expression. Determination of the structures of the protein-nucleic acid recognition and insight into their interactions at molecular level are vital to understanding the regulation function. Recently, quantitative computational approach has been becoming an alternative of experimental technique for predicting the structures and interactions of biomolecular recognition. However, the progress
doi:10.1371/journal.pone.0074443
pmid:24098651
pmcid:PMC3787031
fatcat:wziyj7iqfzejlink6iyywkzyea