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The biological processes that come into play during orthodontic tooth movement (OTM) have been shown to be influenced by a variety of pharmacological agents. The effects of such agents are of particular relevance to the clinician as the rate of tooth movement can be accelerated or reduced as a result. The aim of the present review is to sum-marize the knowledge of these biomarkers which could be used in accelerating or manipulating orthodontic treatment under the effect of routinely prescribeddoi:10.5281/zenodo.3600126 fatcat:3tv2qbfbibhxfip4ljs7yuuw2a