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Appropriate Interferon-alpha Therapy for Chronic Hepatitis C: An Assessment by Quantitative Changes in Serum Hepatitis C Virus-RNA
Internal medicine (Tokyo. 1992)
The antiviral effect of natural interferon (IFN)-oc on chronic hepatitis C virus (HCV) infection was estimated by determining quantitative changes in serum HCV-RNA compared with the serum alanine aminotransferase (SALT) improvement; the relationships of responses to IFN according to the dose and period ofIFN therapy were defined to determine an appropriate IFN therapy protocol. Twenty-two patients with chronic hepatitis C were given natural IFN-a and in 16 (72.7%) patients the viraemia wasdoi:10.2169/internalmedicine.32.523 fatcat:5e6sw2oknffdbn3avtkfenf2bq