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Absorption and Excretion of Drugs. XVII
Absorption and Excretion of Drugs. XVII. Determination of Tetracycline in Urine. (Faculty of Pharmacy, Kyoto University*2) A method for determining urinary concentration of tetracycline was devised by the combination of Permutit column with p-nitrobenzenediazonium chloride reagent. The sample urine is passed through a column of Permutit acidified with hydrochloric acid to adsorb tetracycline on Permutit, this is desorbed with sodium hydroxide solution, and the effluent solution is neutralized.doi:10.1248/yakushi1947.83.3_264 fatcat:pu4hhfrwmvdv7goytqshthquou