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Central position of the human histo (blood) group O(H) and phenotype-determining enzymes in growth and infectious disease
Development of the blood group A phenotype is associated with the impaired formation of adaptive and innate immunoglobulins due to clonal selection and phenotypic, glycosidic accommodation of plasma proteins. Compared with individuals from blood group O(H), individuals with blood group A have a significantly higher risk of developing certain types of cancer and exhibit strong susceptibility to malaria tropica or infection by Plasmodium falciparum. Although malaria tertiana, caused by Plasmodiumdoi:10.6084/m9.figshare.4714618.v247 fatcat:2fmrf2l4sbgd5hjxz6cjnursrm