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Pluribus—Exploring the Limits of Error Correction Using a Suffix Tree
2017
IEEE/ACM Transactions on Computational Biology & Bioinformatics
Next generation sequencing technologies enable efficient and cost-effective genome sequencing. However, sequencing errors increase the complexity of the de novo assembly process, and reduce the quality of the assembled sequences. Many error correction techniques utilizing substring frequencies have been developed to mitigate this effect. In this paper, we present a novel and effective method called PLURIBUS, for correcting sequencing errors using a generalized suffix trie. PLURIBUS utilizes
doi:10.1109/tcbb.2016.2586060
pmid:27362987
pmcid:PMC5754272
fatcat:b25k3nb4hfbt3kruiiouysqrma