Clinical inquiries. Are there big differences among beta-blockers in treating essential hypertension?

Daniel Sontheimer, Kristin Hitchcock, Joseph Saseen
2007 Journal of Family Practice  
multiple, consistent randomized controlled trials [RCTs]). Cardioselective beta-blockers do not alter lung function studies for patients with chronic obstructive pulmonary disease (COPD) or reversible airway disease (SOR: A, meta-analysis of RCTs). Propranolol and timolol have greater risks of causing fatigue as a side effect (SOR: A, metaanalysis of RCTs). Recent meta-analyses have stirred debate on the effectiveness of the agents in preventing adverse outcomes. The level of evidence has
more » ... d the point where the practice of using beta-blockers as monotherapy should be questioned (SOR: C, expert opinion).
pmid:17403332 fatcat:tzj5vmbl25deznnslxlj5boeci