Hepatosplenic T-cell Lymphoma: Case Report & Literature Review

Mariam Al Ghazal
2017 Hematology & Transfusion International Journal  
Hepatosplenic T-cell lymphoma (HSTCL) was first described as a distinct clinicopathologic entity in 1990. HSTCL is more common among young males in their teenage years and in young adulthood. It is an aggressive tumor. Our patient presented with pancytopenia, hepatosplenomegaly but no lymphadenopathy. The key role for diagnosis was through identifying of double negative CD4, CD8 negative lymphocytes with gamma delta T-cells receptor expression. Our case is considered one of the few cases of
more » ... he few cases of hepatosplenic T-cell lymphoma published in Saudi Arabia according to our best of knowledge. The need for high index of suspicion and reporting such rare T-cells lymphomas need to be identified to start therapy properly and early along with understanding more regarding its pathophysiology.
doi:10.15406/htij.2017.05.00111 fatcat:xflibanlgffzpooqsgyhsr27du