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In the past two decades, great efforts have been devoted to extract the dependence and interplay between structure and functions in biological networks because they have strong relevance to biological processes. In this article, we reviewed the recent development in the biological network analysis. In detail, we first reviewed the interactome topological properties of biological networks, the methods for structure and functional patterns.doi:10.1093/bfgp/els045 pmid:23184677 fatcat:uq3hg5ura5a6be2nqua4numfme