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Retinal Growth Hormone: An Autocrine/paracrine in the Developing Chick Retina
The developing chick retina is an extrapituitary site of growth hormone (GH) synthesis and action. GH, GH receptor (GHR) and their mRNAs are present in the neural retina when the neural cells are undergoing proliferation and differentiation during early embryogenesis. It is thus likely that GH acts as an autocrine or paracrine in this location. The present study shows that intra-vitreal injection of a chick GH (cGH) small interfering RNA (siRNA) into the eyes of early embryos [embryonic daydoi:10.7939/r3zw6s fatcat:gxmgmuozfnck7hxigxmbbgs5ji