The Effects of Topical Vitamin C on Burn Wound Healing

Mohammad Haddadi, Department of Nursing, Faculty of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran., Davood Movahedzadeh, Elaheh Jaghouri, Hamid Robat Sarpooshi, Department of Health, Faculty of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran., Department of Nursing, Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences, mashhad, Iran., Department of Nursing, Faculty of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran.
2021 Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk  
and Aim: Topical supplements and vitamins have often been used to accelerate the healing of burn wounds. This study investigated the effects of topical application of vitamin C solution on burn wounds. Methods & Materials: This research was performed on 30 patients with extensive second-degree burns on one or two organs with similar burns. The study subjects were randomly divided into the intervention and control groups. The intervention group received topical application of vitamin C solution
more » ... n addition to silver sulfadiazine ointment in the burn area; however, only silver sulfadiazine ointment was applied in the burn area in the control group. The wounds were examined and scored on days 1, 3, 7, and 14 using the Bates-Jensen Wound Assessment Tool. The collected data were analyzed in SPSS using repeated-measures Analysis of Variance (ANOVA). Ethical Considerations: This study was approved by the ethics committee of sabzevar university medical sciences. (Code: IR.MEDSAB.REC.1394.60). Results Eighteen of the 30 examined patients were male and 12 were female. Their Mean±SD age and body mass index were 43.03±11.90 years and 27.82±4.08 kg/m2, respectively. Conclusion: The repeated-measures ANOVA data indicated that the study groups were significantly different concerning the final mean scores given to the wounds (P=0.047). In other words, the research groups significantly differed in wound healing; thus, topical application of vitamin C significantly improved wound healing in the study participants.
doi:10.32598/jams.24.2.6140.1 fatcat:a3dg4k22ovd3ngxamt3etey2be