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Nitric Oxide Mediates Excitotoxic and Anoxic Damage in Rat Retinal Ganglion Cells Cocultured With Astroglia
1999
Archives of Ophthalmology
Nitric oxide has been implicated in the process of retinal ganglion cell death in glaucoma. Objective: To investigate the role of nitric oxide in mediating retinal ganglion cell death in a culture system that models glial-neuronal interactions at the level of the optic nerve head. Methods: Dissociated retinal ganglion cells from neonatal rats were plated on monolayers of astroglia and identified by retrograde labeling with the fluorescent marker
doi:10.1001/archopht.117.11.1524
pmid:10565522
fatcat:zanpgd243rg3nhh723bjkgyvou