Multivalency effects on Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA

Myriam Bergmann, Gaëlle Michaud, Ricardo Visini, Xian Jin, Emilie Gillon, Achim Stocker, Anne Imberty, Tamis Darbre, Jean-Louis Reymond
2016 Organic and biomolecular chemistry  
The octagalactosylated G3 peptide dendrimer GalAxG3 was obtained by convergent synthesis, bound tightly to lectin LecA, and showed strong Pseudomonas aerguinosa biofilm inhibition and dispersal activity.
doi:10.1039/c5ob01682g pmid:26416170 fatcat:b2fbayvqjrf63chhvkxbmayxe4