A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
WITHDRAWN: Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by N-Terminus Peroxisome Proliferator-Activated Receptor Gamma Coactivator (NT-PGC)-1alpha
Journal of Biological Chemistry
Peroxisomal proliferator activator receptor gamma coactivator (PGC)-1alpha induces both mitochondrial biogenesis and angiogenesis in skeletal muscle. Results: Hypoxic induction of an alternative spliced form of PGC-1alpha induces only angiogenesis in skeletal muscle, and not mitochondrial biogenesis. Conclusion: Alternative splicing of PGC-1alpha explains how PGC-1alpha achieves specific induction of angiogenesis during hypoxia. Significance: The findings suggest novel ways to inducedoi:10.1074/jbc.m113.512061 pmid:24398674 fatcat:ympdatyxdnbixmlblqvmwnqobm