Dynamic modulation of proximity-induced enzyme activity using supramolecular polymers

Eva Magdalena Estirado, Bas Rosier, Tom F. A. de Greef, Luc Brunsveld
2020 Chemical Communications  
Synthetic supramolecular polymers are used as dynamic nanoscaffolds for the activation of the apoptotic signalling enzyme caspase-9. Recruitment of caspase-9 to the nanoscaffold results in an increase in enzymatic activity...
doi:10.1039/d0cc02120b pmid:32319466 fatcat:i6jtlzulyrbrdbw2fcsmmdrrkq