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The Adrenergic Receptors
Adrenergic receptor (AR) signaling is a key regulator of normal cardiopulmonary homeostasis. Under pathophysiological conditions, such as heart failure, asthma, and hypertension, there are alterations in the signaling cascades. Advances in the ability to manipulate the adenoviral genome have allowed the development of gene therapy in which transgenes of interest are inserted into the adenovirus and transferred to mammals in an organ-specific manner based on delivery methods. These transgenesdoi:10.1385/1-59259-931-1:321 fatcat:g5xkeb5xyjba3b347mrnyvlhr4