One pot synthesis of substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-one derivatives

Yellanki Jagannadham, Bhoomireddy Ramadevi, Bethanamudi Prasanna
2017 European Journal of Chemistry  
The title compounds, substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-ones were obtained by reacting 3-aryl-1-(3-coumarinyl)propen-1-ones with 2-napthol catalyzed by DBU (1, 4, 0]undec-7-ene) and concentrated H2SO4 in ample yields. Their structures were characterized by IR, 1 H NMR, 13 C NMR, mass spectral and elemental analysis. All the synthesized compounds have been evaluated for their in-vitro antibacterial activity against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa
more » ... and antifungal activity against Aspergillus Niger and Candida albicans by using serial broth dilution method. Among those compounds 3 band 3c exhibits prominent results.
doi:10.5155/eurjchem.8.1.42-45.1519 fatcat:y7nyxunygngi5lrxnxgppelguu