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The amygdala plays key roles in emotion and social cognition, but how this translates to face-toface interactions involving real people remains unknown. Here we found that a patient with complete amygdala lesions lacks any sense of personal space. Furthermore, healthy individuals showed amygdala activation to close personal proximity. The amygdala may be required to trigger the strong emotional reactions normally following personal space violations, thus regulating interpersonal distance indoi:10.1038/nn.2381 pmid:19718035 pmcid:PMC2753689 fatcat:lvkwfjkqerd5hbau7vutbgk3be