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The Influence of Various Drags on Mortality of Mice and the Concentration of Proinflammatory Cytokines in Blood at Sepsis Caused by E. Coli
2018
Advancements in Case Studies
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Experiments on albino mice showed that administration m-cholinomimetic (aceclydine), n-cholinomimetic (nicotine), reversible inhibitor of acetylcholinesterase (neostigmine methyl sulfate), n-cholinomimetic α7nAChRs agonist (GTS-21), epinephrine hydrochloride, adenomimetic β2ARs agonist (hexaprenaline sulfate) causes decrease in mice mortality in sepsis caused by the administration (i.p.) of E. coli O157:H7 and the concentration of TNF-α, IL-1β and IL-6 in the blood in comparison with parameters at sepsis without use of drugs.
doi:10.31031/aics.2018.01.000512
fatcat:asunbtkkw5dvdeqni4f2y2ogua